Реализация международных образовательных программ как условие развития полиязычной образовательной среды

Вызовы интернационализации высшего образования и науки ставят перед вузами-участниками "Проекта 5-100" задачи создания и развития полиязычной среды, которая позволит увеличить количество публикаций в международных журналах, будет способствовать разработке образовательных продуктов на английском языке для привлечения иностранных студентов и повышению мобильности студентов ипреподавателей университета. Привлечение и адаптация лучших образовательных практик зарубежных университетов способствует формированию профессиональных компетенций научно-педагогических работников университета в области преподавания на английском языке, разрабатывать образовательные курсы на основе современных международных стандартов. Опыт ТПУ в области реализации совместных образовательных программ с Университетом Саутгемптона (Великобритания), осуществляемых с 2012 г., позволяет улучшить качество выполнения задач развития университета в рамках Программы повышения конкурентоспособности ТПУ, учесть специфику профессиональной деятельности обучаемых - преподавателей-предметников, ведущих или планирующих вести занятия на английском языке и сконцентрироваться на разработке образовательных курсов на английском языке для магистратуры и бакалавриата, в том числе для программ с двойным дипломом

Prognosis of Sentinel Node Staged Patients with Primary Cutaneous Melanoma

Background: This study investigated survival probabilities and prognostic factors in sentinel lymph node biopsy (SLNB) staged patients with cutaneous melanoma (CM) with the aim of defining subgroups of patients who are at higher risk for recurrences and who should be considered for adjuvant clinical trials.\ud \ud Methods: Patients with primary CM who underwent SLNB in the Department of Dermatology, University of Tuebingen, Germany, between 1996 and 2009 were included into this study. Survival probabilities and prognostic factors were evaluated by Kaplan-Meier and multivariate Cox proportional hazard models.\ud \ud Results: 1909 SLNB staged patients were evaluated. Median follow-up time was 44 months. Median tumor thickness was 1.8 mm, ulceration was present in 31.8% of cases. The 5-year Overall Survival (OS) was 90.3% in SLNB negative patients (IB 96.2%, IIA 87.0%, IIB 78.1%, IIC 72.6%). Patients with micrometastases (stage IIIA/B) had a 5-year OS rate of 70.9% which was clearly less favorable than for stages I–II. Multivariate analysis revealed tumor thickness, ulceration, body site, histopathologic subtype and SLNB status as independent significant prognostic factors.\ud \ud Conclusion: Survival rates of patients with primary CM in stages I–II were shown to be much more favorable than previously reported from non sentinel node staged collectives. For future clinical trials, sample size calculations should be adapted using survival probabilities based on sentinel node staging

German S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma" – long version of the update 2023

Actinic keratosis (AK) are common lesions in light-skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease burden, especially among the elderly. To establish an evidence-based framework for clinical decision making, the guideline “actinic keratosis and cutaneous squamous cell carcinoma” was updated and expanded by the topics cutanepus squamous cell carcinoma in situ (Bowen’s disease) and actinic cheilitis. This guideline was developed at the highest evidence level (S3) and is aimed at dermatologists, general practitioners, ear nose and throat specialists, surgeons, oncologists, radiologists and radiation oncologists in hospitals and office-based settings, as well as other medical specialties, policy makers and insurance funds involved in the diagnosis and treatment of patients with AK and cSCC